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Positive systems, which are systems whose states are always non-negative, can have both positive linear and positive nonlinear approximations that are valid dynamical models in a prescribed domain. When a linearization of a nonlinear system in a domain near an operating point is equivalent to another linear system representation, a reference-tracking controller for that linear system should also achieve reference-tracking control of the nonlinear system in that domain. Here, we show that only if a linearized positive nonlinear system (PNS) is a positive system (i.e., the PNS is cooperative) will a reference-tracking controller for an equivalent positive linear system realization achieve similar results on the nonlinear system. For an example noncooperative PNS of human blood coagulation, where a published reference-tracking controller assumed a positive linear plant, we develop feedforward and feedback controllers that augment the prior controller to overcome noncooperativity and similarly control the positive nonlinear model.